If your ASP.NET site receives the following error message:
Configuration Error
Description: An error occurred during the processing of a configuration file required to service this request. Please review the specific error details below and modify your configuration file appropriately.
Parser Error Message: It is an error to use a section registered as allowDefinition='MachineToApplication' beyond the application level. This error can be caused by a virtual directory not being configured as an application in IIS.
If your site is running off a subfolder like(http://www.domain.com/application/), then it's very likely that your subfolder is not an asp.net application. To fix this, you can log in to your smarterasp.net control panel-> ASP.NET Manager and set your subfolder as an application.